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The role of Vitamin D in beta-cell function

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PhD title: The role of Vitamin D in beta-cell function.Graduate student: Sue Lynn LauPerformers: Members of the Diabetes & Transcription Factors Lab GroupSynopsis: Every PhD begins in the dark, but it takes only a few bright sparks to kindle the flame of discovery...The crucial role of sunlight exposure as the most important source of vitamin D in humans is highlighted. Vitamin D is newly recognised to be involved in the function of many organ systems, including the beta cells of the endocrine pancreas. These cells make insulin in response to glucose stimulation. Initially, the beta cells are in an unstimulated state, with minimal activity. At the arrival of the sugar plum fairy (symbolising glucose), the cells are able to sense the presence of glucose through the enzyme glucokinase. When glucose enters the cells through glut 2 transporters (marshmallow feeding), it is metabolised to produce the energy molecule, ATP. Through a number of steps, this leads to a rise in positive charge inside the cell, which ultimately triggers the export of insulin-storing granules by a process known as exocytosis (depicted here by the blowing of bubbles). Normal insulin secretion requires the coordinated function of beta cells via intercellular connections and communications as they work in concert. We are investigating whether vitamin D has an effect in improving beta-cell function and increasing insulin secretion... are they "walking on sunshine"??

Channel: Science & Technology
Uploaded: December 31, 1969 at 3:59 pm
Author: lilyforest110

Length: 04:47
Rating: 4.53
Views: 79726

Tags: Dance  PhD  

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Video Comments

klschmidt (December 31, 1969 at 3:59 pm)
Any portion of right-brain use is a good thing. This is awesome! Makes me want to go for a PhD just so I can end up doing the dance number. :-D
DiamonDie (December 31, 1969 at 3:59 pm)
Awesome. Vitamin D. <3
parkcheesi (December 31, 1969 at 3:59 pm)
haha chill dude--Google: Dance your way to a phdLooks like they were "recreating their PhD dissertation for an interpretive dance contest. I'm sure the actual science of the beta-vitamin-D-whatever research is way over our heads. They're clearly doing this for fun... I like it a lot
georgezimmer (December 31, 1969 at 3:59 pm)
the girl is hotter than the sun
arabeea (December 31, 1969 at 3:59 pm)
HA! Brilliant.
cognosco2000 (December 31, 1969 at 3:59 pm)
As a social scientist, let me say that we could definitely do with such activities in our work. Even I understood the meaning of the dance! The only issue though is that Dr Sue is I have to say quite hot as she dances, and thus a bit of a distraction. :-)
tt0the (December 31, 1969 at 3:59 pm)
...That fly over anyBody elseSes head Or was it just me???
arfywarfy (December 31, 1969 at 3:59 pm)
Onefatbass - interpretive dance IS NOT SCIENCE. Oh sure, the dance and music are nice but you tell me what this has to do with getting a PhD in ANYTHING other than the arts? You may want to look in the mirror yourself - don;t be too shocked at the low IQ clown face looking back at you.
etnelav (December 31, 1969 at 3:59 pm)
epic procrastination
wrinkleypp (December 31, 1969 at 3:59 pm)
That was very creative. The sun man is so funny, if sunshine was a man, it would look like him :P

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